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Medical AI · Eyecare & Oculomics

AI That
Sees More

AI-powered solutions delivering smarter eyecare and deeper health insights—helping clinicians make better, evidence-based decisions at scale.

Founded in partnership with

Moorfields Eye Hospital NHS Foundation Trust UCL Institute of Ophthalmology Topcon Healthcare, Inc.

Our Mission

Transforming Eye Disease Detection with AI

At Cascader, we harness the power of artificial intelligence to help clinicians — in hospitals and in primary care — optimise workflows and deliver better patient care.

Our mission is to use AI to enable safe, evidence-based decisions in high-volume, high-risk eye conditions, preventing avoidable sight loss.

We also harness oculomics for non-invasive, early detection of systemic diseases — driving a shift toward preventative healthcare.

May 2025
Officially launched by Moorfields Eye Hospital, UCL IoO, and Topcon Healthcare — a milestone in AI-driven eyecare
Evidence-Led
Every model built on extensive peer-reviewed research and rigorous clinical validation from world-leading institutions
Oculomics
Retinal imaging as a window into systemic health — cardiovascular disease, neurodegeneration, and dementia

The Name Behind the Vision

Inspired by Nature's Most Exceptional Vision

Our name, Cascader, was inspired by the vision of a cascading progression of use cases—starting with eye disease and expanding into systemic health applications.

Cascaders are a type of dragonfly drawn to fast-moving water (cascades), known for their exceptional vision—including 360-degree sight and the ability to see ultraviolet and infrared light.

In disease, a cascade of biological events often leads to organ damage and symptoms. Early detection enables early intervention. Like our namesake, Cascader can fly against the flow of this cascade, using our AI's exceptional vision to detect problems early.

Cascader. AI That Sees More.
Clinical Evidence

Built on World-Class Research

Our AI is evidence-led—built on extensive peer-reviewed research and rigorous clinical validation to prioritise patient safety and measurable clinical outcomes.

JAMA Ophthalmology

Validation and Clinical Applicability of Whole-Volume Automated Segmentation of OCT in Retinal Disease Using Deep Learning

2021 Read publication
Nature Medicine

Clinically Applicable Deep Learning for Diagnosis and Referral in Retinal Disease

2018 Read publication
Eye — Nature Springer

Dual Site External Validation of AI-Enabled Treatment Monitoring for Neovascular Age-Related Macular Degeneration in England

2025 Read publication
Executive Team

Guided by Clinicians & Engineers

Cascader's founding team brings together deep expertise across clinical, technical, and operational domains to deliver real-world solutions at scale.

Dr. Peter Thomas
Chief Executive Officer

Dr. Peter Thomas

Dr Peter Thomas brings extensive experience in developing and delivering innovative healthcare services powered by technology, leading digital transformation programmes, and holding executive and national leadership roles within the NHS.

LinkedIn
Prof. Pearse Keane
Chief Medical Advisor

Prof. Pearse Keane

Professor Pearse Keane is a top expert in eye-related artificial intelligence and Oculomics. He has done important research at Moorfields and UCL IoO. He helped create RETFound, the first major model for eye care, and has done a lot of work to shape the area of Oculomics.

LinkedIn
Ege Ilicak
Chief Operating Officer

Ege Ilicak

Ege Ilicak, Chief Operating Officer, brings 15+ years of experience in the medical engineering field, from hands-on software development to managing large-scale projects and building quality management systems to bring healthcare innovations successfully to market.

LinkedIn
Our Partners

World-Class Institutional Backing

"

This new venture represents the next step in our commitment to translating world-class clinical research into tangible benefits for patients and the NHS.

Peter Ridley

Chief Executive, Moorfields Eye Hospital

"

Cascader reflects our shared vision of how AI and ocular data can reshape eyecare and enable new frontiers in precision medicine.

Ali Tafreshi

CEO, Topcon Healthcare

"

Partnering with industrial leaders in the new area of oculomics should accelerate routes to market for AI technologies and break down the barriers of AI applications in healthcare.

Mark Fisher

Associate Director, UCLB

Moorfields Eye Hospital NHS Foundation Trust
NHS — National Health Service
Topcon Healthcare
UCL University College London
News & Events

Latest from Cascader

Updates from our publications, product launches, and industry collaborations.

Research Publication September, 2025

Reinventing the Eye Exam with Artificial Intelligence

Keane, P.A. Reinventing the eye exam with artificial intelligence. Nat Med (2025).

Pearse A. Keane’s Nature Medicine piece, Reinventing the eye exam with artificial intelligence, outlines how ophthalmology — buoyed by ubiquitous OCT imaging and large-scale datasets — is poised for transformative AI-driven change.

Keane traces progress from the 2018 Moorfields–UCL–DeepMind study to newer foundation-model work (RETFound) and the INSIGHT imaging bioresource, now holding tens of millions of ophthalmic images, which together enable diagnostic automation and “oculomics” insights.

He emphasises the hard work of translating algorithms into routine care — the shift from “idea → algorithm” to “code → clinic” — and highlights Cascader, a May 2025 Moorfields–UCL–Topcon venture he co-founded to accelerate clinical deployment. The article centres on patient impact as the ultimate measure of progress.

Read the article

Upcoming Events

Aug
18–21

IPS XXVIth Visual Field & Imaging Symposium

Bern, Switzerland · 2026
Oct
1–4

26th Euretina Congress

Vienna, Austria · 2026
Product Roadmap

Our Path Forward

We'd like to share a glimpse of our current developments — and how we see Cascader enhancing healthcare in the months ahead.

1
Phase 1

Macular Decision Support

In Development
2
Phase 2

Macular and Glaucoma Disease Support

Coming Soon
3
Phase 3

Cardiovascular and Neurological Oculomic Disease Detection

On the Horizon

Get in Touch

Contact Our Team

For partnerships, product enquiries, press, research collaborations, or general questions — we'd love to hear from you.

info@cascader.ai